LOVD - Variant listings for TNFRSF10A

About this overview [Show]

Patient data (#0000130)
Patient ID
Disease Ovarian cancer
Reference Horak et al., 2005
Template DNA
Technique PCR
Frequency -
Remarks 97 ovarian cancer samples were investigated along with controls. In all three polymorphisms no significant difference could be found between the normal and disease samples.

Variant data
Allele Unknown
Reported pathogenicity Unknown
Concluded pathogenicity Unknown
External ID dbSNP
Exon 4
DNA change c.626G>C   (View in UCSC Genome Browser, Ensembl)
Type Substitution
Mutation effect Missense
Protein p.(Arg209Thr)
PolyPhen 2 Benign
Frequency -
DB-ID TNFRSF10A_00003

3 entries in TNFRSF10A

Path.
Allele Descending
Ascending
External ID Descending
Ascending
Exon Descending
Ascending
DNA change Descending
Ascending
Type Descending
Ascending
Mutation effect Descending
Ascending
Protein Descending
Ascending
PolyPhen 2 Descending
Ascending
Frequency Descending
Ascending
DB-ID Descending
Ascending
?/? Unknown dbSNP 3 c.422A>G Substitution Missense p.(His141Arg) Possibly damaging - TNFRSF10A_00002
?/? Unknown dbSNP 4 c.626G>C Substitution Missense p.(Arg209Thr) Benign - TNFRSF10A_00003
?/? Unknown dbSNP 10 c.1322G>A Substitution Missense p.(Arg441Lys) Benign - TNFRSF10A_00001