LOVD - Variant listings for TNFRSF10A

About this overview [Show]

Patient data (#0000131)
Patient ID
Disease -
Reference Chen et al., 2009
Template -
Technique -
Frequency -
Remarks This paper was an evidence based meta-analysis looking at a total of nine studies. Overall, all three polymorphisms were found to be associated with cancer risk.

Variant data
Allele Unknown
Reported pathogenicity Unknown
Concluded pathogenicity Unknown
External ID dbSNP
Exon 5
DNA change c.683A>C   (View in UCSC Genome Browser, Ensembl)
Type Substitution
Mutation effect Missense
Protein p.(Glu228Ala)
PolyPhen 2 Possibly damaging
Frequency -
DB-ID TNFRSF10A_00005

3 entries in TNFRSF10A

Path.
Allele Descending
Ascending
External ID Descending
Ascending
Exon Descending
Ascending
DNA change Descending
Ascending
Type Descending
Ascending
Mutation effect Descending
Ascending
Protein Descending
Ascending
PolyPhen 2 Descending
Ascending
Frequency Descending
Ascending
DB-ID Descending
Ascending
?/? Unknown dbSNP 4 c.626G>C Substitution Missense p.(Arg209Thr) Benign - TNFRSF10A_00003
?/? Unknown dbSNP 5 c.683A>C Substitution Missense p.(Glu228Ala) Possibly damaging - TNFRSF10A_00005
?/? Unknown dbSNP 10 c.1322G>A Substitution Missense p.(Arg441Lys) Benign - TNFRSF10A_00001