LOVD - Variant listings for TNFRSF10B

About this overview [Show]

Patient data (#0000010)
Patient ID
Disease -
Reference Pai et al., 1998
Template -
Technique -
Frequency -
Remarks This variant is associated with the loss of apoptotic function in head and neck cancer.

The variant was originally reported as NM_147187.2:c.1063_1064dup

Variant data
Allele Unknown
Reported pathogenicity Unknown
Concluded pathogenicity Unknown
Exon 9
DNA change c.1150_1151dup   (View in UCSC Genome Browser, Ensembl)
External ID -
Type Duplication
Mutation effect Frameshift
Protein p.(Met385Argfs*3)
PolyPhen 2 Not determined
Frequency -
DB-ID TNFRSF10B_00010

1 entry in TNFRSF10B

Path.
Allele Descending
Ascending
Exon Descending
Ascending
DNA change Descending
Ascending
External ID Descending
Ascending
Type Descending
Ascending
Mutation effect Descending
Ascending
Protein Descending
Ascending
PolyPhen 2 Descending
Ascending
Frequency Descending
Ascending
DB-ID Descending
Ascending
?/? Unknown 9 c.1150_1151dup - Duplication Frameshift p.(Met385Argfs*3) Not determined - TNFRSF10B_00010