LOVD - Variant listings for TNFRSF10B

About this overview [Show]

Patient data (#0000019)
Patient ID 44
Disease Non-small cell lung cancer (NSCLC)
Reference Lee et al., 1999
Template DNA
Technique PCR, SSCA
Frequency -
Remarks This somatic variant appears to be associated with an increased life span of cancer cells in non-small cell lung cancers (NSCLC).

Variant data
Allele Unknown
Reported pathogenicity Unknown
Concluded pathogenicity Unknown
Exon 9
DNA change c.1087C>T   (View in UCSC Genome Browser, Ensembl)
External ID -
Type Substitution
Mutation effect Missense
Protein p.(Leu363Phe)
PolyPhen 2 -
Frequency -
DB-ID TNFRSF10B_00018

1 entry in TNFRSF10B

Path.
Allele Descending
Ascending
Exon Descending
Ascending
DNA change Descending
Ascending
External ID Descending
Ascending
Type Descending
Ascending
Mutation effect Descending
Ascending
Protein Descending
Ascending
PolyPhen 2 Descending
Ascending
Frequency Descending
Ascending
DB-ID Descending
Ascending
?/? Unknown 9 c.1087C>T - Substitution Missense p.(Leu363Phe) - - TNFRSF10B_00018