LOVD - Variant listings for TNFRSF10B

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Patient data (#0000054)
Patient ID
Disease Hepatocellular carcinoma
Reference Jeng and Hsu, 2002
Template DNA
Technique PCR
Frequency -
Remarks These variants do not appear to be significantly associated with the carcinogenesis of hepatocellular carcinomas.

Variant data
Allele Unknown
Reported pathogenicity Unknown
Concluded pathogenicity Unknown
Exon 2
DNA change c.200C>T   (View in UCSC Genome Browser, Ensembl)
External ID dbSNP
Type Substitution
Mutation effect Missense
Protein p.(Ala67Val)
PolyPhen 2 Possibly damaging
Frequency -
DB-ID TNFRSF10B_00001

4 entries in TNFRSF10B

Path.
Allele Descending
Ascending
Exon Descending
Ascending
DNA change Descending
Ascending
External ID Descending
Ascending
Type Descending
Ascending
Mutation effect Descending
Ascending
Protein Descending
Ascending
PolyPhen 2 Descending
Ascending
Frequency Descending
Ascending
DB-ID Descending
Ascending
?/? Unknown 1 c.95C>T dbSNP Substitution Missense p.(Pro32Leu) Benign - TNFRSF10B_00003
?/? Unknown 2 c.200C>T dbSNP Substitution Missense p.(Ala67Val) Possibly damaging - TNFRSF10B_00001
?/? Unknown 5 c.572T>C dbSNP Substitution Missense p.(Val191Ala) Benign - TNFRSF10B_00011
?/? Unknown 9 c.1223C>T dbSNP Substitution Missense p.(Thr408Met) Probably damaging - TNFRSF10B_00013