LOVD - Variant listings for TNFRSF10B

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Patient data (#0000119)
Patient ID 5
Disease Non-small cell lung cancer (NSCLC)
Reference Lee et al., 1999
Template DNA
Technique PCR, SSCA
Frequency -
Remarks This somatic variant appears to be associated with an increased life span of cancer cells in non-small cell lung cancers (NSCLC).

Variant data
Allele Unknown
Reported pathogenicity Unknown
Concluded pathogenicity Unknown
Exon 9
DNA change c.1062G>A   (View in UCSC Genome Browser, Ensembl)
External ID NHLBI Exome Sequencing Project
Type Substitution
Mutation effect Nonsense
Protein p.(Trp354*)
PolyPhen 2 Not determined
Frequency A=1/G=10757
DB-ID TNFRSF10B_00047

1 entry in TNFRSF10B

Path.
Allele Descending
Ascending
Exon Descending
Ascending
DNA change Descending
Ascending
External ID Descending
Ascending
Type Descending
Ascending
Mutation effect Descending
Ascending
Protein Descending
Ascending
PolyPhen 2 Descending
Ascending
Frequency Descending
Ascending
DB-ID Descending
Ascending
?/? Unknown 9 c.1062G>A NHLBI Exome Sequencing Project Substitution Nonsense p.(Trp354*) Not determined A=1/G=10757 TNFRSF10B_00047